Photodynamic effects of erythrosine on the smooth muscle cells of guinea-pig taenia coli
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چکیده
منابع مشابه
Desensitization of smooth muscle cells in the guinea pig taenia coli to prolonged application of carbachol.
depolarized the membrane, reduced the membrane resistance and evoked contracture. These responses did not, however, continue but a desensitization to Carb then developed, i. e. the membrane was gradually repolarized, membrane resistance increased, and the muscle relaxed in spite of the presence of Carb. 2. During the repolarization phase in the presence of Carb (10-5 g/ml), repeated current pul...
متن کاملOutward current in single smooth muscle cells of the guinea pig taenia coli
In single myocytes of the guinea pig taenia coli, dispersed by enzymatic digestion, the late outward current is carried by K+. It has both a Ca2+-activated component and a voltage-dependent component which is resistant to external Co2+. The reversal potential is -84 mV, and the channel(s) for it are highly selective to K+. At 33 degrees C, the activation follows n2 kinetics, with a voltage-depe...
متن کاملInward current in single smooth muscle cells of the guinea pig taenia coli
Using the tight-seal voltage-clamp method, the ionic currents in the enzymatically dispersed single smooth muscle cells of the guinea pig taenia coli have been studied. In a physiological medium containing 3 mM Ca2+, the cells are gently tapering spindles, averaging 201 (length) x 8 microns (largest diameter in center of cell), with a volume of 5 pl. The average cell capacitance is 50 pF, and t...
متن کاملThe Effects of Temperature and Some Drugs on the Ionic Movements in the Smooth Muscle of Guinea-pig Taenia Coli.
There have been many papers concerning the potassium and sodium movements of the excitable tissues such as squid giant axon'), frog sartorius,2s) rat diaphragm4) and mammalian heart muscle5) by means of radioactive tracers. Also on the smooth muscle tissue, since the experiment of Born & Biilbring (1956)6), numerous works have been performed on the sodium, potassium or calcium movement in this ...
متن کاملThe Differences in the Relaxant Effects of Different Fractions of Rosa damascena on Guinea Pig Tracheal Smooth Muscle
Objective(s) In the present study, the differences in the relaxant effects of aqueous, ethyl acetate and n-butanol fractions of Rosa damascena on tracheal smooth muscle of guinea pigs were examined. Materials and Methods The relaxant effects of three cumulative concentrations of each fraction (0.1, 0.2 and 0.4 g%) in comparison with saline and three cumulative concentrations of theophylline ...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1984
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1984.tb16520.x